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Around 150 people are feared dead after a plane crashed in the French Alps.
Flight 4U9525 disappeared from radar around 45 minutes after leaving Barcelona in Spain for Dusseldorf in Germany at 10am local time.
It is believed to have come down in the Digne area of southern France.
French President Francois Hollande confirmed the crash and said he expects there to be "no survivors".
Reports suggest there were 142 passengers and six crew on board.
'Crash site only accessible via helicopter'
The plane appears to have come down in a very remote area near a ski resport.
Germanwings has scheduled a press conference for 3pm today.
The Spanish President Mariano Rajoy has just tweeted about the "tragedy".
"Dismayed by the air accident in the Alps. A tragedy. We're working with the French and German authorities on the investigation," he wrote.
Plane flew exact same route yesterday
A look through flight logs by AirLive.net shows that flight 4U9525 took the exact same route from Barcelona to Dusseldorf yesterday.
Reports suggest the plane has come down in a "crevice" which is inaccessible from the road.
The Spanish press is reporting that there were 42 Spaniards on board the flight.
'Our thoughts are with those affected' - Airbus
Airbus has just tweeted a statement on today's tragedy.
The firm says it will provide further information as soon as possible and passes on its thoughts to those affected.
Due to the mountainous nature of the crash site, the French Interior Minister has said he expects the recovery operation to be "an extremely long and extremely difficult".
<blockquote class="twitter-tweet" lang="en"><p>We will provide further information as soon as available. Our thoughts are with those affected by this tragic event.</p>— Airbus (@Airbus) <a href="https://twitter.com/Airbus/status/580335590970900480">March 24, 2015</a></blockquote>